Journal Club of the Week: Compusyn Software for Drugs Analysis

In the 13th February 2017, journal club meeting, the theoretical aspects of CompuSyn Software were discussed. The method, median effect equation, combination index, and the equations used in this statistical technique/method were described. It was mentioned that this method is used to evaluate the synergism, potentiation, and antagonism in combination therapies. It is used for a single drug and drug combinations pharmacodynamics with automated simulations, for dose-effect data analysis of enzymes, receptors, microorganisms, cells, animals and clinical trials. The measurement of IC50, IC95, ED50, LD10, LD50 were explained.