Journal Club of the week: An overview about possible Acrylamide toxicity


Journal Club 11-01-2016

Speaker Name: Ms. Tina Didari (PhDs)

Topic: An overview about possible Acrylamide toxicity

In the today journal meeting Tina Didari introduced the participants to acrylamide. How it is metabolized in the liver and excretes through kidney from the body as well as its possible toxicity. She talked about acrylamide use in waste water treatment, gel electrophoresis, paper making, ore processing, tertiary oil recovery, and the manufacturing of fabrics. Some acrylamide is used in the manufacturing of dyes and other monomers. She also told that how acrylamide has many other uses in molecular biology laboratories, including the use of linear polyacylamide as a carrier, which aids in the precipitation of small amounts of DNA. Still up to 2015, it is unclear whether acrylamide consumption affects people's risk of developing cancer. That acrylamide is considered a potential occupational carcinogen and classified as a group 2A Carcinogen by the IARC. Acrylamide was discovered accidentally in foods in April 2002 by scientists in Sweden when they found the chemical in starchy foods, such as potato crisps, French fries (chips), and bread that had been heated higher than 120 °C (248 °F) (production of acrylamide in the heating process was shown to be temperature-dependent). It was not found in food that had been boiled or in foods that were not heated. Acrylamide is neurotoxic and genotoxic in nature as well. At the end all participants asked their valuable questions and gave some suggestions for improving her editorial. The presenter answered all the questions and will follow the suggestions of participants. 

At last but not the least, Mohammad Amin Rezvanfar the PhDc recited a few verses of the Holy Quran (book) by the request of Prof Abdollahi.